| No. Registro | 002857364 |
| Tipo de material | ARTIGO DE PERIODICO - INTERNACIONAL |
| Cód. publicação |  10.1007/s00125-013-3058-y DOI |
| Entrada Principal | Soulimane, Soraya (*) INT França |
| Título | HbA1c, fasting and 2 h plasma glucose in current, ex- and never-smokers: a meta-analysis. |
| Imprenta | Berlin, 2013. |
| Descrição | p. 30-39. |
| Idioma | Inglês |
| Nota | Disponível em:<http://dx.doi.org/10.1007/s00125-013-3058-y>. Acesso em: 01 nov. 2017 |
| Assunto | GLICOSE -- METABOLISMO |
| | TABAGISMO |
| | JEJUM |
| | METANÁLISE |
| Autor Secundário | Simon, Dominique (*) INT Inserm, CESP Centre for Research in Epidemiology and Population Health, U1018, Epidemiology of diabetes, obesity and chronic kidney diseases over the lifecourse, Villejuif França |
| | Herman, William (*) INT University of Michigan, Ann Arbor, Michigan Estados Unidos |
| | Lange, Celine (*) INT Inserm, CESP Centre for Research in Epidemiology and Population Health, U1018, Epidemiology of diabetes, obesity and chronic kidney diseases over the lifecourse, Villejuif França |
| | Lee, Crystal M. Y (*) INT The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders, University of Sydney, Sydney Austrália |
| | Colagiuri, Stephen (*) INT The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders, University of Sydney, Sydney Austrália |
| | Shaw, Jonathan E (*) INT Baker IDI Heart and Diabetes Institute, Melbourne Austrália |
| | Zimmet, Paul Z (*) INT Baker IDI Heart and Diabetes Institute, Melbourne Austrália |
| | Magliano, Dianna (*) INT Baker IDI Heart and Diabetes Institute, Melbourne Austrália |
| | Ferreira, Sandra R. G. |
| Fonte | In: Diabetologia, Berlin, v. 57, n. 1, p. 30-39, 2013, ISSN: 0012-186X |
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| Resumo/Outros | AIMS/HYPOTHESIS: The relationships between smoking and glycaemic variables have not been well explored. We compared HbA1c, fasting plasma glucose (FPG) and 2 h plasma glucose (2H-PG) in current, ex- and never-smokers. METHODS: This meta-analysis used individual data from 16,886 men and 18,539 women without known diabetes in 12 DETECT-2 consortium studies and in the French Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) and Telecom studies. Means of three glycaemic variables in current, ex- and never-smokers were modelled by linear regression, with study as a random factor. The I (2) statistic was used to evaluate heterogeneity among studies. RESULTS: HbA1c was 0.10% (95% CI 0.08, 0.12) (1.1 mmol/mol [0.9, 1.3]) higher in current smokers and 0.03% (0.01, 0.05) (0.3 mmol/mol [0.1, 0.5]) higher in ex-smokers, compared with never-smokers. For FPG, there was no significant difference between current and never-smokers (-0.004 mmol/l [-0.03, 0.02]) but FPG was higher in ex-smokers (0.12 mmol/l [0.09, 0.14]). In comparison with never-smokers, 2H-PG was lower (-0.44 mmol/l [-0.52, -0.37]) in current smokers, with no difference for ex-smokers (0.02 mmol/l [-0.06, 0.09]). There was a large and unexplained heterogeneity among studies, with I (2) always above 50%; I (2) was little changed after stratification by sex and adjustment for age and BMI. In this study population, current smokers had a prevalence of diabetes that was 1.30% higher as screened by HbA1c and 0.52% lower as screened by 2H-PG, in comparison with never-smokers. CONCLUSION/INTERPRETATION: Across this heterogeneous group of studies, current smokers had a higher HbA1c and lower 2H-PG than never-smokers. This will affect the chances of smokers being diagnosed with diabetes |
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| Acervo Geral | Todos os itens |
| Itens na Biblioteca | FSP-Faculdade de Saúde Públi |
| Unidade USP | FSP -- FAC DE SAÚDE PÚBLICA |
